Data were collected from April 13, 2009, to October 31, 2011, and were analyzed from November 20, 2019, to March 4, 2020. The institutional review board of Saint Luke’s Mid America Heart Institute approved the study, and the institutional review boards of the participating medical centers (eAppendix in the Supplement) waived the requirement for patient written informed consent because this study’s analyses were done within a study to improve the process of informed consent this study was deemed a quality improvement initiative. This cohort study was conducted in accordance with the Strengthening the Reporting of Observational Studies in Epidemiology ( STROBE) reporting guideline. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine. Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.Combined medical and invasive strategies left 28.5% of patients still symptomatic at the end of the study. No difference between invasive and medical groups was found at 12 months in symptoms, quality of life and MACEs, except for a greater improvement in self-assessed symptoms in the invasive group. Among these, 38.2% had normal coronary arteries and 47% actually underwent revascularization. After one month of medical therapy, 40.6% of patients were referred for coronary angiography and revascularization for resistant symptoms (invasive strategy). The rate of MACEs was low (2.9%) in the overall population. Patients in CCS class I significantly increased from 28.4% at enrollment to 67.1% at 12 months, and the SAQ-7 score from 58.4 ± 20 to 85.9 ± 14. After one month of therapy, angina relieved or improved in 47% of the overall population. Upon enrollment, all patients were prescribed guidelines directed medical therapy. A composite end-point of MACEs (all-cause death, non-fatal myocardial infarction, non-fatal stroke or hospitalization for unstable angina) at 1 year was considered. Symptoms and quality of life were evaluated with the CCS angina grading, with a self-assessment scale and with the SAQ-7. Eight hundred thirty-three patients with newly diagnosed, stable angina were enrolled in a prospective, observational, nationwide registry and followed for 1 year.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. Archives
March 2023
Categories |